"Both President Obama and President Zardari acknowledged that more work needed to be done to address the direct threat to our countries posed by terrorist groups in Pakistan," the statement said.
Mr Obama, who has already announced he will travel to Pakistan in 2011 and will host Mr Zardari at the White House, "emphasised the United States' commitment and support for democracy and transparency in Pakistan," the statement added.
Mr Obama "also acknowledged Pakistan's economic difficulties, and encouraged President Zardari to work to pass key economic reforms, such as tax reform and containing energy subsidies," the White House said.
The US president "concluded the call by conveying his intention to visit Pakistan in 2011 and personally welcomed President Zardari to visit the United States in the coming year."
The leaders' talks came after three days of strategic dialogue between the two nations. The United States last week offered Pakistan a two-billion-dollar arms package but warned it will not tolerate human rights abuses.
On Friday Secretary of State Hillary Clinton said the US administration would ask Congress to approve two billion dollars in military aid from 2012 to 2016, replacing an earlier five-year package that expired.
The five-year assistance plan satisfies a key request of Pakistan's influential military, which assists the US military in Afghanistan and was initially uneasy about a US shift to civilian assistance.
